It doesn't sound good Skip but don't give up just yet.

Interesting read: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2942055/

I'm betting the tick is coincidental, but it could have played a role in the dogs weakened immune system. Along with the topical drugs. I say that about topical drugs because what are these chemicals we are trusting to cover all of these things systemically? It just seems we really don't know all of the side effects yet.

However this turns out it's a learning lesson for us all. Please keep the updates coming.

S_B