Quote Originally Posted by SteelyDan View Post
From some research I did which I can't seem to find...

They had high success rates with prostaglsmdins combined with muscle relaxers and abx. Maybe talk to your vet about that. The study suggested an 80% survival rate with that and a 37% rate of getting pups on future breedings.

Those who have used prostaglandins like Lutalyse before know how dangerous giving them to a closed case of pyo can be. Talking ruptured uterus. Bad way to die.
I saved a bitch with an open pyometra with prostaglandin about 2 years ago. The treatment itself almost killed her. The vet I used then, said to hit her with it and the next morning, if no "bad discharge", hit her again and do this until it was finished. I had to hit her 3 times. Each time, was terrible. The vomiting and what it does to the dog is way worse than the actual infection.....or appears to be. It did save her life and uterus. However, I honestly do not believe she'll ever have a pup. She's had 4 heat cycles since then. All very weak, no swelling, no flagging. I bred her on one where she "kinda" flagged, nothing.

Best of luck mound.....I'd like to know the suggest treatment for a closed one. The only closed I had, I put down.