Anytime a bulldog doesn't eat for 2 days, it needs a vet.
Surprised you haven't heard of pyometra yet; it's a killer and it's fairly common in elder bitches.
Anytime any bitch comes out of heat (bred or not), you need to be aware of the potential for pyometra.
Lethargy, inappetence, bloat, tremendous thirst, etc. are all telltale signs.
I am sorry for your loss, but I am even sorrier your bitch had to go through all that for so long, without reprieve, because you didn't do anything. It is an agonizing way to go for them.
Jack





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